BDBM725540 3-(4- ((difluoro- methyl)sulfon- amido)-3-(1-(4- fluorophenyl) cycloprop- oxy)phenyl)-5-((5- methylpyrazin-2- yl)amino)- 1H-pyrazole- 4-carboxamide::US20250074891, Compound 290

SMILES Cc1cnc(Nc2[nH]nc(-c3ccc(NS(=O)(=O)C(F)F)c(OC4(c5ccc(F)cc5)CC4)c3)c2C(N)=O)cn1

InChI Key InChIKey=GQHFSVVNWSMQDT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 725540   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725540(3-(4- ((difluoro- methyl)sulfon- amido)-3-(1-(4- f...)
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725540(3-(4- ((difluoro- methyl)sulfon- amido)-3-(1-(4- f...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM725540(3-(4- ((difluoro- methyl)sulfon- amido)-3-(1-(4- f...)
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent