BDBM725559 (S)-3-(4- ((difluoromethyl)sulfonamido)-3-(1-(4- fluorophenyl)ethoxy)phenyl)-5-((2- methylpyrimidin-4-yl)amino)-1H- pyrazole-4-carboxamide::US20250074891, Compound 309::US12583836, Compound 309
SMILES Cc1nccc(Nc2[nH]nc(-c3ccc(NS(=O)(=O)C(F)F)c(O[C@@H](C)c4ccc(F)cc4)c3)c2C(N)=O)n1
InChI Key InChIKey=IDQAPOONDXTXHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 725559
Affinity DataKd: <10nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Affinity DataKd: <10nMAssay Description:Cryopreserved human PBMCs from healthy donors were thawed and resuspended in RPMI-1640 media with L-glutamine (Corning) supplemented with 10% Fetal B...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Kinase assays. For most assays, kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 stra...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Cryopreserved human PBMCs from healthy donors were thawed and resuspended in RPMI-1640 media with L-glutamine (Corning) supplemented with 10% Fetal B...More data for this Ligand-Target Pair
Affinity DataKd: >3.00E+4nMAssay Description:Human peripheral blood mononuclear cells (PBMCs) consist of lymphocytes, monocytes and dendritic cells that express TLR7, TLR8 and TLR9. These cells ...More data for this Ligand-Target Pair