BDBM725651 US20250074895, Compound 32

SMILES CN(C)c1cnc(Nc2cc([C@H]3CC[C@@H](OC(=O)NC4(C)CC4)C3)[nH]n2)cn1

InChI Key InChIKey=NJGZXUZWJCOWTA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 725651   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM725651(US20250074895, Compound 32)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM725651(US20250074895, Compound 32)
Affinity DataIC50: 500nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent