BDBM725677 US20250074895, Compound 58

SMILES COc1nccc(Nc2cc([C@@H]3CC[C@H](OC(=O)NC4(C)CC4)C3)[nH]n2)n1

InChI Key InChIKey=AILCRVZOLXYMSZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 725677   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM725677(US20250074895, Compound 58)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Blueprint Medicines

US Patent
LigandPNGBDBM725677(US20250074895, Compound 58)
Affinity DataIC50: 100nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent