BDBM725827 US20250074911, Example 50

SMILES COc1ccc(F)cc1C(=O)NCc1ccc(-c2nn3c4c(cnc(N)c24)/C=C/CCCC(=O)N[C@@H]2CCC[C@@H]3C2)cc1

InChI Key InChIKey=YTMYIRKODKMZDL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 725827   

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725827(US20250074911, Example 50)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725827(US20250074911, Example 50)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent