BDBM725828 US20250074911, Example 51

SMILES COc1ccc(F)cc1C(=O)NCc1ccc(-c2nn3c4c(cnc(N)c24)/C=C/CCCCC(=O)N[C@@H]2CCC[C@@H]3C2)cc1

InChI Key InChIKey=AEHLPIIBOULALW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 725828   

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725828(US20250074911, Example 51)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725828(US20250074911, Example 51)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent