BDBM725837 US20250074911, Example 60

SMILES C[C@@H]1CCn2nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c3c(N)ncc(c32)/C=C/CCCCCC(=O)N1

InChI Key InChIKey=GRJJFEADJRUWSB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 725837   

TargetTyrosine-protein kinase BTK(Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725837(US20250074911, Example 60)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on wt-BTK enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent

TargetTyrosine-protein kinase BTK [C481S](Human)
Crossfire Oncology Holding

US Patent
LigandPNGBDBM725837(US20250074911, Example 60)
Affinity DataIC50: 5nMAssay Description:To determine the inhibitory activity of compounds on BTK C481S enzyme activity, the IMAP® assay (Molecular Devices) was used. Compounds were serially...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/10/2025
Entry Details
US Patent