BDBM726503 6-chloro-5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-vi)methyl]piperazin-1-yl]-N-methyl-pyridine-2-carboxamide::US20250082630, Example 8
SMILES CCC1=Nc2ccc(CN3CCN(c4ccc(C(=O)NC)nc4Cl)CC3)c(Cl)c2CC1=O
InChI Key InChIKey=BBZFZQCABMRZBW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 726503
Affinity DataIC50: 4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+4nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair