BDBM726505 5-[4-[(5-chloro-2-ethyl-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N-methyl-pyridine-2-carboxamide::US20250082630, Example 10
SMILES CCC1=Nc2ccc(CN3CCN(c4ccc(C(=O)NC)nc4)CC3)c(Cl)c2CC1=O
InChI Key InChIKey=JABLAUFGTMTLDO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 726505
Affinity DataIC50: 13nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair