BDBM726536 6-chloro-5-[4-[(5-fluoro-2-methoxy-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N-methyl-pyridine-2-carboxamide::US20250082630, Example 41
SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(OC)c(=O)[nH]c4c3F)CC2)c(Cl)n1
InChI Key InChIKey=NAGZIAQPWXFHRJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 726536
Affinity DataIC50: 5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair