BDBM726553 6-fluoro-5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinoxalin-6-yl)methyl]piperazin-1-yl]-N-methyl-pyridine-2-carboxamide::US20250082630, Example 58

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(OC)c(=O)[nH]c4c3C)CC2)c(F)n1

InChI Key InChIKey=ZLTNQLOPLKNGPU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 726553   

TargetPoly [ADP-ribose] polymerase 1(Human)
Astrazeneca

US Patent
LigandPNGBDBM726553(6-fluoro-5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinox...)
Affinity DataIC50: 8nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Astrazeneca

US Patent
LigandPNGBDBM726553(6-fluoro-5-[4-[(2-methoxy-5-methyl-3-oxo-4H-quinox...)
Affinity DataIC50: 1.00E+5nMAssay Description:Recombinant full length 6HIS tagged PARP1 protein was diluted to 6 nM with 50 mM Tris pH 8, 0.001% Triton X100, 10 mM MgCl2, 150 mM NaCl and incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/16/2025
Entry Details
US Patent