BDBM726687 (1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydroxypropan-2-yl)-1-isopropyl-1H- benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)-6,8- dioxabicyclo[3.2.1]octan-4-ol::US20250084095, Compound 1

SMILES CC(C)n1c(C(C)(C)O)nc2c(F)cc(-c3nc(NC4C[C@H]5CO[C@H](O5)[C@H]4O)ncc3Cl)cc21

InChI Key InChIKey=XMTXXRRXTXBUMH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 726687   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726687((1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydro...)
Affinity DataIC50: 3.15nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726687((1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydro...)
Affinity DataIC50: 63.8nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726687((1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydro...)
Affinity DataIC50: 4.88E+3nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726687((1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydro...)
Affinity DataIC50: 2.62E+4nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Accutar Biotechnology

US Patent
LigandPNGBDBM726687((1S,3R,4S,5R)-3-((5-chloro-4-(4-fluoro-2-(2- hydro...)
Affinity DataIC50: 3.00E+4nMAssay Description:This ADP-Glo assay measures ADP formed from a kinase reaction and indirectly quantifies the phosphorylation of peptide substrates by the CDK/cyclin p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/17/2025
Entry Details
US Patent