BDBM727038 N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-(trifluoromethyl)imidazolidin-1-yl]methyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-3-(1-methylcyclopropyl)isoxazole-4-carboxamide::US12252491, Example 14

SMILES CC1(c2nocc2C(=O)N[C@H](c2cn3ncc(CN4C[C@@H](C(F)(F)F)NC4=O)cc3n2)C2CCC(F)(F)CC2)CC1

InChI Key InChIKey=JLNXCCGAHBKYQI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 727038   

LigandPNGBDBM727038(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 36.1nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent