BDBM728116 (Z)-2-((1-acetyl- 3-oxoindolin-2- ylidene)methyl)- 4-(naphthalen-2- yl)quinoline-6- carboxylic acid::US20250091994, Example 157

SMILES CC(=O)n6c(=Cc4cc(c2ccc1ccccc1c2)c3cc(C(=O)O)ccc3n4)c(=O)c5ccccc56

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728116   

LigandPNGBDBM728116((Z)-2-((1-acetyl- 3-oxoindolin-2- ylidene)methyl)-...)
Affinity DataIC50: 600nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent