BDBM728132 (Z)-1-acetyl-2-((4- (1-ethyl-1H-pyr- azol-4-yl)-6- (morpholine-4- carbonyl)quinolin- 2-yl)methylene)- indolin-3-one::US20250091994, Example 178
SMILES CCn1cc(-c2cc(/C=C3/C(=O)c4ccccc4N3C(C)=O)nc3ccc(C(=O)N4CCOCC4)cc23)cn1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728132
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 800nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
