BDBM728147 (Z)-1-acetyl-2- ((4-(2-acetyl- 1,2,3,4-tetra- hydroisoquinolin- 5-yl)quinolin-2- yl)methylene)- indolin-3-one::US20250091994, Example 193
SMILES CC(=O)N1CCc2c(cccc2-c2cc(/C=C3/C(=O)c4ccccc4N3C(C)=O)nc3ccccc23)C1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 728147
TargetRAF proto-oncogene serine/threonine-protein kinase [50-131]/GTPase KRas [G12V](Human)
Kobe University
US Patent
Kobe University
US Patent
Affinity DataIC50: 700nMAssay Description:The in vitro Ras-Raf binding inhibitory activity of the compound of the present invention was evaluated by an ELISA method described below. GST-c-Raf...More data for this Ligand-Target Pair
