BDBM728212 US20250092029, Compound AP-8-013

SMILES O=C(CN1C(=O)[C@@H](NC(=O)OCc2ccccc2)COc2ccccc21)N[C@@H](C[C@@H]1CCNC1=O)C(=O)COC(=O)c1c(Cl)cccc1Cl

InChI Key InChIKey=MCPZPZYQLAPBPU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 728212   

TargetReplicase polyprotein 1ab [3235-3246](HCoV-NL63)
The Wistar Institute of Anatomy and Biology

US Patent
LigandPNGBDBM728212(US20250092029, Compound AP-8-013)
Affinity DataIC50: 230nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetCathepsin B(Human)
The Wistar Institute of Anatomy and Biology

US Patent
LigandPNGBDBM728212(US20250092029, Compound AP-8-013)
Affinity DataIC50: 1.80E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetProcathepsin L(Human)
The Wistar Institute of Anatomy and Biology

US Patent
LigandPNGBDBM728212(US20250092029, Compound AP-8-013)
Affinity DataIC50: 3.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent

TargetProthrombin(Human)
The Wistar Institute of Anatomy and Biology

US Patent
LigandPNGBDBM728212(US20250092029, Compound AP-8-013)
Affinity DataIC50: 3.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
Go to US Patent