BDBM728255 US20250092039, Compound 50

SMILES CCc1c(F)ccc2cc(O)cc(-c3ncc4c(N5CCC[C@@](C)(O)C5)nc(OCC5(CN6CCC7(CC6)CC(N6CCN(c8cc(F)c(C9CCC(=O)NC9=O)c(F)c8)CC6)C7)CC5)nc4c3F)c12

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728255   

TargetGTPase KRas [G12V]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Tiger Biotherapeutics

US Patent

LigandBDBM728255(US20250092039, Compound 50)Copy SMILES

Affinity DataIC50: 160nMAssay Description:Briefly, for the KRAS-G12V/RAF1 binding assay, 2 nM GppNHp-bound 6*His tagged KRAS-G12V proteins or 2 nM GDP-bound 6*His tagged KRAS-G12V proteins (f...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
7/25/2025
Entry Details
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