BDBM728258 US20250092039, Compound 57

SMILES CCc1c(F)ccc2cc(O)cc(-c3ncc4c(N5CCC[C@@](C)(O)C5)nc(OCC5(CN6CCC(N7CC8(CCN(c9cc(F)c(C%10CCC(=O)NC%10=O)c(F)c9)CC8)C7)CC6)CC5)nc4c3F)c12

InChI Key

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728258   

TargetGTPase KRas [G12V]/RAF proto-oncogene serine/threonine-protein kinase(Human)
Tiger Biotherapeutics

US Patent

LigandBDBM728258(US20250092039, Compound 57)Copy SMILES

Affinity DataIC50: 20nMAssay Description:Briefly, for the KRAS-G12V/RAF1 binding assay, 2 nM GppNHp-bound 6*His tagged KRAS-G12V proteins or 2 nM GDP-bound 6*His tagged KRAS-G12V proteins (f...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
7/25/2025
Entry Details
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