BDBM72832 5-(2,4-Dimethyl-phenyl)-3H-thieno[2,3-d]pyrimidin-4-one::5-(2,4-dimethylphenyl)-3H-thieno[2,3-d]pyrimidin-4-one::MLS001204004::SMR000518842::cid_709327

SMILES CN1CCN(c2nc(NCc3ccco3)c3cc(Cl)ncc3n2)CC1

InChI Key InChIKey=GFJWIHBNRAJRJZ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72832   

TargetHistamine H4 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72832BDBM72832(US12492199, Example 4)
Affinity DataIC50: 100nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent

TargetHistamine H1 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72832BDBM72832(US12492199, Example 4)
Affinity DataIC50: 1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent