BDBM728368 (S)-(6-amino-5-(3- hydroxy-2,6- dimethylphenyl)- 2,3-dimethyl-5H- pyrrolo[2,3- b]pyrazin-7-yl)(1H- indol-2- yl)methanone::US20250092052, Example 9

SMILES Cc1nc2c(C(=O)c3cc4ccccc4[nH]3)c(N)n(-c3c(C)ccc(O)c3C)c2nc1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728368   

LigandPNGBDBM728368((S)-(6-amino-5-(3- hydroxy-2,6- dimethylphenyl)- 2...)
Affinity DataIC50: 375nMAssay Description:The reaction buffer was used as a composition of 200 mM Tris-HCl pH 7.4, 100 mM MgCl2, 0.5 mg/mL BSA, 0.25 mM DTT, and the reactions of all the tests...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
7/25/2025
Entry Details
US Patent