BDBM728374 (6-amino-5-(3- hydroxy-2,6- dimethylphenyl)- 5H-pyrrolo[2,3- b]pyrazin-7-yl)(1H- pyrrol-2- yl)methanone::US20250092052, Example 23

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(=O)c2ccc[nH]2)c2nccnc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728374   

LigandPNGBDBM728374((6-amino-5-(3- hydroxy-2,6- dimethylphenyl)- 5H-py...)
Affinity DataIC50: 200nMAssay Description:The reaction buffer was used as a composition of 200 mM Tris-HCl pH 7.4, 100 mM MgCl2, 0.5 mg/mL BSA, 0.25 mM DTT, and the reactions of all the tests...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent