BDBM728399 US20250092056, Compound I-257

SMILES N#CCn1c(N2CC(OC(F)(F)F)C2)c(-c2ccc(F)c(Cl)c2)c(=O)n(-c2cncc(Cl)c2)c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 728399   

TargetReplicase polyprotein 1ab(2019-nCoV)
Shionogi & Co.

US Patent
LigandPNGBDBM728399(US20250092056, Compound I-257)
Affinity DataIC50: 0.350nMAssay Description:In this test, an assay buffer consisting of 20 mM Tris-HCl, 1 mM EDTA, 10 mM DTT, and 0.01% BSA is used. The sample to be tested is diluted in advanc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/25/2025
Entry Details
US Patent