BDBM72871 1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid::1-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]-5-(trifluoromethyl)pyrazole-4-carboxylic acid::1-[4-(3-nitrophenyl)-2-thiazolyl]-5-(trifluoromethyl)-4-pyrazolecarboxylic acid::1-[4-(3-nitrophenyl)thiazol-2-yl]-5-(trifluoromethyl)pyrazole-4-carboxylic acid::MLS001166153::SMR000550165::cid_1482626

SMILES CN1CCN(c2nc(NCCS(=O)(=O)Nc3cccc(C(F)(F)F)c3)c3cc(Cl)ncc3n2)CC1

InChI Key InChIKey=IGDMGZSQPCSPBR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72871   

TargetHistamine H4 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72871BDBM72871(US12492199, Example 78)
Affinity DataIC50: 100nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent