BDBM72883 4-[(4-chlorobenzyl)amino]-6,7-dimethoxy-1H-quinazoline-2-thione::4-[(4-chlorobenzyl)amino]-6,7-dimethoxyquinazoline-2(1H)-thione::4-[(4-chlorophenyl)methylamino]-6,7-dimethoxy-1H-quinazoline-2-thione::MLS001199574::SMR000560297::cid_24761203

SMILES COc1cc2nc(=S)[nH]c(NCc3ccc(Cl)cc3)c2cc1OC

InChI Key InChIKey=YDSSPSDIPKDGQN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 72883   

TargetHistamine H4 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72883BDBM72883(US12492199, Example 93)
Affinity DataIC50: 100nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetHistamine H1 receptor(Human)
Faes Farma

US Patent
LigandChemical structure of BindingDB Monomer ID 72883BDBM72883(US12492199, Example 93)
Affinity DataIC50: 1.00E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay