BDBM729425 N-(3-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)ureido)phenyl)acrylamide::US20250100994, Compound YJZ4156

SMILES C=CC(=O)Nc1cccc(N(C(=O)NCc2ccccc2)[C@H]2CC[C@H](Nc3ccc(C#N)cn3)CC2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729425   

TargetCyclin-dependent kinase 13(Human)
University of Michigan

US Patent
LigandPNGBDBM729425(N-(3-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 275nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
University of Michigan

US Patent
LigandPNGBDBM729425(N-(3-(3-benzyl-1-((1r,4r)-4-((5-cyanopyridin-2-yl)...)
Affinity DataIC50: 500nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent