BDBM72944 3-(benzenesulfonyl)-7-hydroxy-1-benzopyran-2-one::3-(benzenesulfonyl)-7-hydroxychromen-2-one::3-besyl-7-hydroxy-coumarin::7-oxidanyl-3-(phenylsulfonyl)chromen-2-one::MLS001167917::SMR000641128::cid_5639796

SMILES Oc1ccc2cc(c(=O)oc2c1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=WMNPQFZDBBSKIO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 72944   

TargetTyrosine-protein kinase JAK1(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72944BDBM72944(1-methyl-3-((1r,4r)-4- (methyl(7H-pyrrolo[2,3- d]p...)
Affinity DataIC50: 156nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetTyrosine-protein kinase JAK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72944BDBM72944(1-methyl-3-((1r,4r)-4- (methyl(7H-pyrrolo[2,3- d]p...)
Affinity DataIC50: 292nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetTyrosine-protein kinase JAK3(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72944BDBM72944(1-methyl-3-((1r,4r)-4- (methyl(7H-pyrrolo[2,3- d]p...)
Affinity DataIC50: 618nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72944BDBM72944(1-methyl-3-((1r,4r)-4- (methyl(7H-pyrrolo[2,3- d]p...)
Affinity DataIC50: 3.82E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay