BDBM729442 N-(5-(1-((1r,4S)-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-3-(2-fluorobenzyl)ureido)-2-((S)-3,4-dimethylpiperazin-1-yl)phenyl)acrylamide::US20250100994, Compound YJZ9179

SMILES C=CC(=O)Nc1cc(N(C(=O)NCc2ccccc2F)[C@H]2CC[C@H](Nc3ccc(C#N)cn3)CC2)ccc1N1CCN(C)[C@@H](C)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 729442   

TargetCyclin-dependent kinase 13(Human)
University of Michigan

US Patent
LigandPNGBDBM729442(N-(5-(1-((1r,4S)-4-((5-cyanopyridin-2-yl)amino)cyc...)
Affinity DataIC50: 15nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 12(Human)
University of Michigan

US Patent
LigandPNGBDBM729442(N-(5-(1-((1r,4S)-4-((5-cyanopyridin-2-yl)amino)cyc...)
Affinity DataIC50: 32.5nMAssay Description:The inhibitory activities of the test compound on the kinases were evaluated by LANCE Ultra assay, which was used for detecting ATP-dependent phospho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent