BDBM72948 6-chloranyl-N'-[2,3,5,6-tetrakis(fluoranyl)phenyl]pyridine-3-carbohydrazide::6-chloro-N'-(2,3,5,6-tetrafluorophenyl)-3-pyridinecarbohydrazide::6-chloro-N'-(2,3,5,6-tetrafluorophenyl)nicotinohydrazide::6-chloro-N'-(2,3,5,6-tetrafluorophenyl)pyridine-3-carbohydrazide::MLS001233799::SMR000595491::cid_2604242

SMILES CN(c1ncnc2[nH]ccc12)[C@H]1CC[C@H](NC(=O)NCC#N)CC1

InChI Key InChIKey=XZMLWIAYVCHIHQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 72948   

TargetTyrosine-protein kinase JAK1(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72948BDBM72948(1-(cyanomethyl)-3-((1r,4r)-4- (methyl(7H-pyrrolo[2...)
Affinity DataIC50: 7.5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72948BDBM72948(1-(cyanomethyl)-3-((1r,4r)-4- (methyl(7H-pyrrolo[2...)
Affinity DataIC50: 18nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72948BDBM72948(1-(cyanomethyl)-3-((1r,4r)-4- (methyl(7H-pyrrolo[2...)
Affinity DataIC50: 26nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72948BDBM72948(1-(cyanomethyl)-3-((1r,4r)-4- (methyl(7H-pyrrolo[2...)
Affinity DataIC50: 415nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details
US Patent