BDBM72949 5-[(2-ketochromen-7-yl)oxymethyl]furan-2-carboxylic acid isopropyl ester::5-[(2-oxo-1-benzopyran-7-yl)oxymethyl]-2-furancarboxylic acid propan-2-yl ester::MLS001233785::SMR000591108::cid_2517479::propan-2-yl 5-[(2-oxidanylidenechromen-7-yl)oxymethyl]furan-2-carboxylate::propan-2-yl 5-[(2-oxochromen-7-yl)oxymethyl]furan-2-carboxylate

SMILES CC(C)OC(=O)c1ccc(COc2ccc3ccc(=O)oc3c2)o1

InChI Key InChIKey=QGYVROBILFIZDK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 72949   

TargetTyrosine-protein kinase JAK1(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72949BDBM72949(1-((1r,4r)-4-(methyl(7H- pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 2.30nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetTyrosine-protein kinase JAK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72949BDBM72949(1-((1r,4r)-4-(methyl(7H- pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 14nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetTyrosine-protein kinase JAK3(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72949BDBM72949(1-((1r,4r)-4-(methyl(7H- pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 42nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
ChemWerth

US Patent
LigandChemical structure of BindingDB Monomer ID 72949BDBM72949(1-((1r,4r)-4-(methyl(7H- pyrrolo[2,3-d]pyrimidin-4...)
Affinity DataIC50: 335nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2026
Entry Details PCBioAssay