BDBM72973 MLS000936240::SMR000621011::cid_3431377

SMILES COc1ccc2c(c1)C(CC(C#N)NC(=O)C1C3C(CN1C(=O)C(NC(=O)C(F)(F)F)C(C)(C)C)C3(C)C)C(=O)N2

InChI Key InChIKey=UVGGPIRYERVAFM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 72973   

TargetReplicase polyprotein 1ab(2019-nCoV)
Trawsfynydd Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 72973BDBM72973((1S,2S,5S)-N-[(1S)-1-cyano-2-(5-methoxy-2-oxo-indo...)
Affinity DataIC50: 10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2026
Entry Details
US Patent