BDBM729814 US20250101052, Compound 53

SMILES CCc1cc(Nc2ncc(Cl)c(Nc3ccc(C)c(C)c3P(C)(C)=O)n2)c(OC)cc1N1CCC(N2CC3CC(C2)N3C)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 729814   

TargetEpidermal growth factor receptor [T790M,C797S,L858R](Homo sapiens (Human))
Zhejiang University

US Patent
LigandPNGBDBM729814(US20250101052, Compound 53)
Affinity DataIC50: 0.269nMAssay Description:Kinase Reaction Process(1) 1×Kinase buffer was prepared.(2) Preparation of concentration gradient of compound: The tested compound has a test concent...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/31/2025
Entry Details
US Patent