BDBM73006 US12497392, Compound 106

SMILES CO[C@H]1CC[C@H](n2c([C@@H]3CCOCC(=O)N3C3=CC(F)C(F)C=C3)nc3cc(C4C(C)=NOC4C)ccc32)CC1

InChI Key InChIKey=FKZKKUGBWRQBLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 73006   

TargetHistone acetyltransferase p300 [1049-1156](Human)
Hinova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 73006BDBM73006(US12497392, Compound 106)
Affinity DataIC50: 2.20nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2026
Entry Details
US Patent

TargetCREB-binding protein [1085-1192](Human)
Hinova Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 73006BDBM73006(US12497392, Compound 106)
Affinity DataIC50: 4.80nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2026
Entry Details
US Patent