BDBM730087 The Preparation of the Compounds of Examples 210A and 210B::US12263171, Example 210A

SMILES COc1ccc2c(c1)nc(N)n1nc([C@@H]3CC[C@H](C)N(c4cnn(C5CCC[C@H]5O)c4)C3)nc21

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 730087   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM730087(The Preparation of the Compounds of Examples 210A ...)
Affinity DataIC50: 0.200nMAssay Description:148 μL, (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM4001A) and 2 μL compounds of the invention to be tested (test compound) were transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM730087(The Preparation of the Compounds of Examples 210A ...)
Affinity DataIC50: 4.80nMAssay Description:148 μL, (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM4001A) and 2 μL compounds of the invention to be tested (test compound) were transferred t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent