BDBM73042 US12497405, Compound 37

SMILES O=C1OC[C@@H]2C[C@@H](Oc3cc4c(=O)n(Cc5ccc(Cl)cc5)cnc4nc3-c3cnco3)CCN12

InChI Key InChIKey=BCXFNWFSMPMLMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 73042   

TargetMajor DNA-binding protein(HHV-3)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 73042BDBM73042(US12497405, Compound 37)
Affinity DataIC50: 0.220nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2026
Entry Details
US Patent

TargetDNA polymerase catalytic subunit(HHV-5)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 73042BDBM73042(US12497405, Compound 37)
Affinity DataIC50: 1.10nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/27/2026
Entry Details
US Patent