BDBM730538 US20250122174, Example 120

SMILES CC(C)c1nc2c(N3CC[C@@H](N)C3)c(NC(=O)c3nn(-c4c(F)cccc4F)c(=O)cc3Cl)ccc2n1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 730538   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Shenzhen Yuanli Shenwan Innovative Medicine

US Patent
LigandPNGBDBM730538(US20250122174, Example 120)
Affinity DataIC50: 100nMAssay Description:A stock solution of 10 mM test compound was prepared in DMSO. The compound was prepared by 5-fold and 10-point serial dilutions with HPK1 kinase assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent