BDBM731079 3-(2-methoxyphenyl)-N-(6-(4-methylphenyl)thiazolo[4,5-b]pyrazin-2-yl)pyridine-4-carboxamide ::US20250122221, Compound 6

SMILES COc1ccccc1-c1cnccc1C(=O)Nc1nc2ncc(-c3ccc(C)cc3)nc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731079   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731079(3-(2-methoxyphenyl)-N-(6-(4-methylphenyl)thiazolo[...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent