BDBM731088 N-(6-(4-cyano-2-methoxyphenyl)thiazolo[4,5-b]pyrazin-2-yl)-3-(2-methoxyphenyl)isonicotinamide ::US20250122221, Compound 15

SMILES COc1cc(C#N)ccc1-c1cnc2nc(NC(=O)c3ccncc3-c3ccccc3OC)sc2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731088   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731088(N-(6-(4-cyano-2-methoxyphenyl)thiazolo[4,5-b]pyraz...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent