BDBM731091 N-(6-(4-chlorophenyl)thiazolo[4,5-b]pyrazin-2-yl)-6-cyano-4-(2-(difluoromethoxy)phenyl)nicotinamide ::US20250122221, Compound 18

SMILES N#Cc1cc(-c2ccccc2OC(F)F)c(C(=O)Nc2nc3ncc(-c4ccc(Cl)cc4)nc3s2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731091   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731091(N-(6-(4-chlorophenyl)thiazolo[4,5-b]pyrazin-2-yl)-...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent