BDBM731110 N-(6-(4-chlorophenyl)thiazolo[4,5-b]pyrazin-2-yl)-2'',5-dicyano-[1,1''-biphenyl]-2-carboxamide ::US20250122221, Compound 37

SMILES N#Cc1ccc(C(=O)Nc2nc3ncc(-c4ccc(Cl)cc4)nc3s2)c(-c2ccccc2C#N)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731110   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731110(N-(6-(4-chlorophenyl)thiazolo[4,5-b]pyrazin-2-yl)-...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent