BDBM731135 N-(6-(5-chloropyridin-2-yl)thiazolo[4,5-b]pyrazin-2-yl)-4-(5-cyano-2-methoxyphenyl)-6-methylpyridine-3-carboxamide ::US20250122221, Compound 62

SMILES COc1ccc(C#N)cc1-c1cc(C)ncc1C(=O)Nc1nc2ncc(-c3ccc(Cl)cn3)nc2s1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731135   

TargetDNA polymerase theta(Human)
Nanjing Zaiming Pharmaceutical

US Patent
LigandPNGBDBM731135(N-(6-(5-chloropyridin-2-yl)thiazolo[4,5-b]pyrazin-...)
Affinity DataIC50: 100nMAssay Description:Brief introduction to the experimental principle: The N-terminal active peptide segment (MI-N899) of POLQ with ATPase activity was co-incubated with ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/18/2025
Entry Details
US Patent