BDBM731287 US12281080, SCCP 6295

SMILES N#Cc1ccc2nccc(NCCc3ccc4cc(C(=O)N5CCS(=O)CC5)ccc4c3)c2c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731287   

TargetCyclin-dependent kinase 8/19(Human)
University of South Carolina

US Patent
LigandPNGBDBM731287(US12281080, SCCP 6295)
Affinity DataIC50: 5.80nMAssay Description:In vitro binding of the compounds to the ATP pocket of CDK8 in complex with Cyclin C was carried out by LanthaScreen® Eu Kinase Binding Assay based o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/20/2025
Entry Details
US Patent