BDBM731494 3-chloro-5-((1-(5-(1-methyl-6-oxo-1,6-dihydropyridazin-3-yl)-1,2,4-oxadiazol-3-yl)piperidin-4-yl)methyl)benzonitrile ::US12268687, Compound 117

SMILES Cn1nc(-c2nc(N3CCC(Cc4cc(Cl)cc(C#N)c4)CC3)no2)ccc1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 731494   

TargetStearoyl-CoA desaturase 5(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731494(3-chloro-5-((1-(5-(1-methyl-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50: 30nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStearoyl-CoA desaturase(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM731494(3-chloro-5-((1-(5-(1-methyl-6-oxo-1,6-dihydropyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:Samples were then analyzed by LC/MS/MS using a Thermo Scientific Q Exactive Orbitrap coupled to a Dionex UltiMate® 3000 ultra-high performance liquid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent