BDBM731759 (1R,3R)-1-[4-[1-(3,3- dimethoxypropyl)azetidin-3- yl]oxy-2,6-difluoro-phenyl]- 2-(2-fluoro-2-methyl-propyl)- 3-methyl-1,3,4,9- tetrahydropyrido[3,4-b]indole::US20250114338, Example 176

SMILES COC(CCN1CC(Oc2cc(F)c([C@@H]3c4[nH]c5ccccc5c4C[C@@H](C)N3CC(C)(C)F)c(F)c2)C1)OC

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731759   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731759((1R,3R)-1-[4-[1-(3,3- dimethoxypropyl)azetidin-3- ...)
Affinity DataEC50:  0.0310nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent