BDBM731853 3-((1R,3R)-1-(2,6-difluoro-4- (2-(3-(fluoromethyl)azetidin- 1-yl)ethoxy)phenyl)-3- methyl-1,3,4,9-tetrahydro- 2H-pyrido[3,4-b]indol-2-yl)- 2-fluoro-2-methylpropan-1-ol::US20250114338, Example 255

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(OCCN3CC(CF)C3)cc2F)N1CC(C)(F)CO

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 731853   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM731853(3-((1R,3R)-1-(2,6-difluoro-4- (2-(3-(fluoromethyl)...)
Affinity DataEC50:  0.0100nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent