BDBM732100 (S)-3-((1R,3R)-1-(2,6- difluoro-4-((1-(3- fluoropropyl)azetidin-3- yl)amino)phenyl)-3-methyl- 3,4-dihydro-1H-pyrido[3,4- b]indol-2(9H)-yl)-2-fluoro-2- (hydroxymethyl) propanenitrile::US20250114338, Example 419

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1C[C@](F)(C#N)CO

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732100   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM732100((S)-3-((1R,3R)-1-(2,6- difluoro-4-((1-(3- fluoropr...)
Affinity DataEC50:  0.0260nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent