BDBM732111 N-[4-[(1R,3R)-2-(2,2- difluoroethyl)-3-methyl- 1,3,4,9-tetrahydropyrido[3,4- b]indol-1-yl]-3,5-difluoro- phenyl]-1-(3- fluoropropyl)azetidin-3- amine::US20250114338, Example 430

SMILES C[C@@H]1Cc2c([nH]c3ccccc23)[C@@H](c2c(F)cc(NC3CN(CCCF)C3)cc2F)N1CC(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732111   

TargetEstrogen receptor(Human)
Genentech

US Patent
LigandPNGBDBM732111(N-[4-[(1R,3R)-2-(2,2- difluoroethyl)-3-methyl- 1,3...)
Affinity DataEC50:  0.0650nMAssay Description:All of the exemplary Formula I compounds in Tables 1 and 2 were tested for binding to ERa (Estrogen Receptor alpha) and biological activity according...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
8/22/2025
Entry Details
US Patent