BDBM732817 5-[5-chloro-4-fluoro-2-[(3S)-3- (morpholinomethyl)-3,4-dihydro-1H- isoquinoline-2-carbonyl]phenyl]-N-(4- cyanophenyl)-N-[(3-methoxy-2-methyl- phenyl)methyl]-1,2-dimethyl-pyrrole-3- carboxamide::US20250115577, Compound 29

SMILES COc1cccc(CN(C(=O)c2cc(-c3cc(Cl)c(F)cc3C(=O)N3Cc4ccccc4C[C@H]3CN3CCOCC3)n(C)c2C)c2ccc(C#N)cc2)c1C

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 732817   

TargetApoptosis regulator Bcl-2(Human)
Eil Therapeutics

US Patent
LigandPNGBDBM732817(5-[5-chloro-4-fluoro-2-[(3S)-3- (morpholinomethyl)...)
Affinity DataIC50: 30nMAssay Description:BPS Bioscience, #50222: 3 ng of BCL-2, 5 μL of 1:100 anti-His Tb-labeled donor, 5 μL of 1:100 Dye-labeled acceptor, 5 L of 1:40 BCL-2 Peptide Ligand,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent