BDBM733110 US20250115590, Compound PC-48

SMILES Cc1cc(COc2ccc(Sc3ccncc3C3NC(=O)NC3=O)cc2C)ccn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 733110   

TargetMacrophage metalloelastase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetMacrophage metalloelastase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 10nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetCollagenase 3(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 550nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStromelysin-2(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetMatrix metalloproteinase-9(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetNeutrophil collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetStromelysin-1(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

Target72 kDa type IV collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 1.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetMatrix metalloproteinase-14(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 5.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetMatrilysin(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 5.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent

TargetInterstitial collagenase(Human)
Foresee Pharmaceuticals USA

US Patent
LigandPNGBDBM733110(US20250115590, Compound PC-48)
Affinity DataIC50: 5.00E+3nMAssay Description:The inhibitory effect of compounds on the rate of cleaving fluorogenic MMP substrate (Enzo, BML-P128) by recombinant human MMP-12 catalytic domain (E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent