BDBM733511 (2S,4R)-1-[(2S)-2-{7-[4-(4-amino-3-{4- ethanesulfonamido-3-[(4- fluorophenyl)methoxy]phenyl}-1H- pyrazolo[4,3-c]pyridin-7-yl)-1H-pyrazol-1- yl]heptanamido}-3,3-dimethylbutanoyl]-4- hydroxy-N-{[4-(4-methyl-1,3-thiazol-5- yl)phenyl]methyl}pyrrolidine-2-carboxamide From Intermediate F3. LCMS (method D): 1.86 min, m/z: 1049.4 [M + H]+, 525.2 [M + 2H]2+.::US20250115598, Compound 1003

SMILES CCS(=O)(=O)Nc1ccc(-c2n[nH]c3c(-c4cnn(CCCCC(=O)N[C@H](C(=O)N5C[C@H](O)C[C@H]5C(=O)NCc5ccc(-c6scnc6C)cc5)C(C)(C)C)c4)cnc(N)c23)cc1OCc1ccc(F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 733511   

TargetMixed lineage kinase domain-like protein(Human)
Anaxis Pharma

US Patent
LigandPNGBDBM733511((2S,4R)-1-[(2S)-2-{7-[4-(4-amino-3-{4- ethanesulfo...)
Affinity DataKd: <50nMAssay Description:Binding affinity of the test compounds for human MLKL (full length), mouse MLKL (full length), human RIPK1 and human RIPK3 was determined using the K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/22/2025
Entry Details
US Patent